Interacting effects of exercise with breaks in sitting time on cognitive and metabolic function in older adults: Rationale and design of a randomised crossover trial

Abstract

Background: A single bout of moderate-to-vigorous intensity exercise improves both metabolic and cognitive function. In addition to exercise, emerging evidence suggests that reducing sitting time may be another strategy for improving metabolic function. However, the combined effects of acute exercise with reductions in sitting time on cognitive and metabolic function are largely unknown. Methods/design: This is a dual-site randomised crossover trial involving three acute experimental conditions separated by a minimum six-day washout period. This trial included physically inactive and sedentary older adults (55–80 years) who were overweight to obese (body mass index 25–45 kg/m2). Participants..